Kaposi sarcoma herpesvirus inflammatory cytokine syndrome–like clinical presentation in human immunodeficiency virus–infected children in Malawi
NK El-Mallawany, W Kamiyango… - Clinical Infectious …, 2019 - academic.oup.com
Clinical Infectious Diseases, 2019•academic.oup.com
We describe 7 human immunodeficiency virus–infected Malawian children with Kaposi
sarcoma who met criteria for Kaposi sarcoma herpesvirus (KSHV) inflammatory cytokine
syndrome. Each presented with persistent fevers, bulky lymphadenopathy, massive
hepatosplenomegaly, and severe cytopenias. Plasma analyses were performed in 2
patients, both demonstrating extreme elevations of KSHV viral load and interleukin 6.
sarcoma who met criteria for Kaposi sarcoma herpesvirus (KSHV) inflammatory cytokine
syndrome. Each presented with persistent fevers, bulky lymphadenopathy, massive
hepatosplenomegaly, and severe cytopenias. Plasma analyses were performed in 2
patients, both demonstrating extreme elevations of KSHV viral load and interleukin 6.
Abstract
We describe 7 human immunodeficiency virus–infected Malawian children with Kaposi sarcoma who met criteria for Kaposi sarcoma herpesvirus (KSHV) inflammatory cytokine syndrome. Each presented with persistent fevers, bulky lymphadenopathy, massive hepatosplenomegaly, and severe cytopenias. Plasma analyses were performed in 2 patients, both demonstrating extreme elevations of KSHV viral load and interleukin 6.
Oxford University Press