A novel CCDC39 mutation causes multiple morphological abnormalities of the flagella in a primary ciliary dyskinesia patient
D Chen, Y Liang, J Li, X Zhang, R Zheng… - Reproductive …, 2021 - Elsevier
Research question Male infertility is a widespread symptom in patients with primary ciliary
dyskinesia (PCD). PCD-related male infertility is often caused by asthenozoospermia, with
barely normal sperm morphology. Multiple morphological abnormalities of the sperm flagella
(MMAF) are a major cause of asthenozoospermia, characterized by various malformed
morphologies of sperm flagella. To date, a limited number of genes have been suggested to
be involved in the pathogenesis of both PCD and MMAF. What other genes associated with …
dyskinesia (PCD). PCD-related male infertility is often caused by asthenozoospermia, with
barely normal sperm morphology. Multiple morphological abnormalities of the sperm flagella
(MMAF) are a major cause of asthenozoospermia, characterized by various malformed
morphologies of sperm flagella. To date, a limited number of genes have been suggested to
be involved in the pathogenesis of both PCD and MMAF. What other genes associated with …
